Subject(s)
Adolescent , Adult , Exocrine Pancreatic Insufficiency , Female , Humans , Male , Mouth Abnormalities , SyndromeABSTRACT
Chronic diarrhea and steatorrhea occur frequently in patients with autoimmune polyglandular syndrome (APS) type I. Intestinal lymphangiectasia has been reported earlier as a cause of steatorrhea in a young girl with APS Type I. We describe 2 patients with APS Type I who were found to have intestinal lymphangiectasia, one of whom had symptomatic protein-losing enteropathy.
Subject(s)
Adult , Diagnosis, Differential , Fatal Outcome , Female , Humans , Lymphangiectasis, Intestinal/diagnosis , Male , Polyendocrinopathies, Autoimmune/complicationsABSTRACT
A 52 yrs old male presented with multiple, painless, firm nodules over extremities, which were mimicking benign neoplastic lesion. Fine needle aspiration was performed from three such nodules which revealed chalky white aspirate. After staining the smears with H&E and Giemsa stains, smears show amorphous pink material, needle shaped crystalline structures, many macrophages and foreign body type giant cells. A diagnosis of gouty tophi was offered which was confirmed by histopathology and serum uric acid level.
Subject(s)
Biopsy, Fine-Needle , Crystallization , Extremities , Giant Cells, Foreign-Body/pathology , Gout/diagnosis , Histocytochemistry , Humans , Male , Middle Aged , Uric Acid/bloodABSTRACT
A 45-year-old male presented with severe abdominal pain, hyperamylasaemia and a bulky pancreas. In addition, he had deep jaundice and markedly raised serum transaminases, and his serum was positive for IgM anti-hepatitis E virus (HEV) antibodies. The common aetiologies of acute pancreatitis were excluded. The patient ran a benign course for both acute viral hepatitis and acute pancreatitis, and recovered completely. Acute pancreatitis caused by HEV infection has been reported only occasionally.
Subject(s)
Acute Disease , Hepatitis E/complications , Humans , Male , Middle Aged , Pancreatitis/diagnosisABSTRACT
Intussusception of the intestine is rare in adults. We report a case of a 45-year-old male who presented with long-standing pyrexia of unknown origin, abdominal pain, gastrointestinal bleeding and constitutional symptoms. Colonoscopic examination revealed a large invaginated mass suggestive of colonic intussusception due to gastrointestinal stromal tumour of the colon. His symptoms disappeared after surgical removal of the tumour.
Subject(s)
Colonic Neoplasms/complications , Humans , Intussusception/diagnosis , Leiomyosarcoma/complications , Male , Middle AgedABSTRACT
Dubin-Johnson syndrome is neither complicated by liver cell necrosis nor associated with portal hypertension. We report a 22-year-old man who had recurrent episodes of jaundice (conjugated hyperbilirubinemia) because of Dubin-Johnson syndrome and portal hypertension secondary to portal vein thrombosis. The relationship between Dubin-Johnson syndrome and portal vein thrombosis in this case is most likely a chance occurrence.
Subject(s)
Adult , Hemophilia A/genetics , Humans , Hypertension, Portal/etiology , Jaundice, Chronic Idiopathic/complications , Male , Point Mutation , Portal Vein/pathology , Venous Thrombosis/complicationsABSTRACT
Plummer Vinson syndrome is a constellation of postcricoid esophageal webs, iron deficiency anemia, dysphagia and koilonychia. We describe some unusual manifestations in three patients with this syndrome; these were clubbing instead of koilonychia, tortuous esophagus in addition to presence of esophageal webs, and celiac disease.